منابع مشابه
Aggressive B-Cell Lymphomas
Aggressive B-cell lymphomas (ABLs) are a group of B-cell malignancies, that is, a relatively common form of cancer across the world. This issue on aggressive B-cell lymphomas compiles 12 exciting manuscripts, most of which are very meticulously performed reviews of the available current literature. Three areas of lymphoma pathology and biology that are leading to a greater understanding of rela...
متن کاملMolecular Profiling of Aggressive Lymphomas
In the last years, several studies of molecular profiling of aggressive lymphomas were performed. In particular, it was shown that DLBCL can be distinguished in two different entities according to GEP. Specifically, ABC and GCB subtypes were characterized by having different pathogenetic and clinical features. In addition, it was demonstrated that DLBCLs are distinct from BL. Indeed, the latter...
متن کاملPrognostic Factors in Aggressive Non-Hodgkin's Lymphomas.
Aggressive non-Hodgkin's lymphoma (NHL) is a biologically heterogeneous disease that can be cured with aggressive chemotherapy treatment. Different clinical, biological, cellular and molecular features have been identified as having prognostic significance on the outcome of NHL patients. The knowledge of these prognostic features can be used in everyday practice in order to predict the prognosi...
متن کاملAggressive Non-Hodgkin’s Lymphomas in Immunocompromised
During the period from 1981 through 1984. 14 immunocompromised homosexual males with intermediate or high-grade non-Hodgkin’s lymphoma were seen at University of Texas M.D. Anderson Hospital and Tumor Institute. Six patients had diffuse large-cell lymphoma. seven had diffuse undifferentiated lymphoma. and one had unclassifiable lymphoma that suggested large-cell lymphoma. Eight patients had the...
متن کاملFailure of conventional chemotherapy in aggressive lymphomas.
Between 1975 and 1982 in 2 centres in Glasgow, 53 previously untreated patients with aggressive non-Hodgkin's lymphomas received chemotherapy consisting of one of the following regimens-CVP, MOPP, CHOP or BACOP. Twenty nine patients (55%) entered complete remission (CR), 20 (38%) had partial remission (PR) and 4 (7%) had progressive disease (PD). Of the 29 patients in CR, 9 have relapsed and di...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2010
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmra0807082